Andrew W Roberts Selected Research

Therapeutics

4/2024	Seven-year outcomes of venetoclax-ibrutinib therapy in mantle cell lymphoma: durable responses and treatment-free remissions.
4/2024	Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers.
1/2023	Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia.
11/2022	Single-cell multiomics reveal the scale of multilayered adaptations enabling CLL relapse during venetoclax therapy.
1/2022	Many Medicare Beneficiaries Do Not Fill High-Price Specialty Drug Prescriptions.
1/2022	Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL.
11/2021	Predictors of Chronic Opioid Use: A Population-Level Analysis of North Carolina Cancer Survivors Using Multi-Payer Claims.
1/2021	Introduction to a review series on small-molecule targeted therapies for lymphoid malignancies.
1/2021	Long-term Follow-up of Patients with Relapsed or Refractory Non-Hodgkin Lymphoma Treated with Venetoclax in a Phase I, First-in-Human Study.
1/2021	Efficacy of venetoclax plus rituximab for relapsed CLL: 5-year follow-up of continuous or limited- duration therapy.

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Andrew W Roberts Research Topics

Disease

41	Neoplasms (Cancer) 04/2024 - 10/2002
30	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2024 - 02/2012
14	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2023 - 05/2015
11	Multiple Myeloma 12/2023 - 01/2009
9	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 04/2024 - 04/2008
9	Leukemia 01/2021 - 10/2006
7	Lymphoma (Lymphomas) 04/2024 - 11/2008
6	Hematologic Neoplasms (Hematological Malignancy) 04/2024 - 12/2015
6	Opioid-Related Disorders (Opiate Addiction) 01/2023 - 10/2016
6	B-Cell Lymphoma (Lymphoma, B Cell) 01/2022 - 01/2016
6	Disease Progression 01/2021 - 06/2016
6	Thrombocytopenia (Thrombopenia) 01/2021 - 10/2006
6	Inflammation (Inflammations) 05/2014 - 08/2004
5	Residual Neoplasm 12/2023 - 02/2017
5	Breast Neoplasms (Breast Cancer) 06/2023 - 01/2019
5	Pain (Aches) 12/2021 - 04/2015
5	Lymphadenopathy 11/2019 - 05/2005
4	Substance-Related Disorders (Drug Abuse) 01/2022 - 10/2016
4	Cancer Pain 12/2020 - 01/2020
4	Infections 01/2020 - 01/2012
4	Rheumatoid Arthritis 01/2016 - 08/2004
4	Splenomegaly 04/2015 - 02/2004
4	Experimental Arthritis 01/2012 - 08/2004
3	Neutropenia 01/2021 - 03/2005
3	Opiate Overdose 01/2021 - 01/2019
3	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2021 - 03/2017
3	Arthritis (Polyarthritis) 12/2008 - 08/2004
2	Anemia 01/2021 - 04/2015
2	Tumor Lysis Syndrome 10/2018 - 02/2017
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2016 - 03/2010
2	Autoimmune Diseases (Autoimmune Disease) 02/2013 - 08/2010
2	Graft vs Host Disease (Graft-Versus-Host Disease) 07/2010 - 07/2003
2	Thrombocytosis (Thrombocythemia) 03/2007 - 05/2005
1	Bites and Stings (Sting) 04/2024
1	Thrombotic Thrombocytopenic Purpura 01/2024
1	Thrombotic Microangiopathies 01/2024
1	Hepatitis C 01/2022
1	Diarrhea 01/2022
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Fever (Fevers) 01/2022
1	Hypercholesterolemia 01/2022
1	Hypertension (High Blood Pressure) 01/2022
1	Sepsis (Septicemia) 01/2022
1	Atrial Fibrillation 01/2022
1	Immune System Diseases (Immune Disorders) 01/2022
1	Diabetes Complications 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	COVID-19 01/2021
1	Cytopenia 01/2021
1	Colorectal Neoplasms (Colorectal Cancer) 01/2021
1	Waldenstrom Macroglobulinemia (Macroglobulinemia) 10/2020

Drug/Important Bio-Agent (IBA)

46	venetoclaxIBA 04/2024 - 02/2013
19	Proteins (Proteins, Gene)FDA Link 04/2024 - 07/2008
11	Opioid Analgesics (Opioids)IBA 12/2021 - 04/2015
7	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2008 - 10/2002
6	ibrutinibIBA 04/2024 - 01/2018
6	CytokinesIBA 01/2016 - 05/2005
6	navitoclaxIBA 01/2016 - 03/2010
5	Interleukin-6 (Interleukin 6)IBA 01/2012 - 05/2005
4	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 10/2020
4	zanubrutinibIBA 01/2022 - 12/2019
4	Rituximab (Mabthera)FDA Link 05/2021 - 09/2015
3	Naloxone (Narcan)FDA LinkGeneric 01/2022 - 01/2019
3	Prednisolone (Predate)FDA LinkGeneric 12/2021 - 04/2009
3	Bortezomib (Velcade)FDA Link 01/2020 - 04/2008
3	ABT-737IBA 03/2010 - 11/2006
2	Buprenorphine (Subutex)FDA LinkGeneric 01/2023 - 01/2018
2	Myeloid Cell Leukemia Sequence 1 ProteinIBA 11/2020 - 11/2017
2	Cytarabine (Cytosar-U)FDA LinkGeneric 10/2020 - 05/2017
2	S63845IBA 01/2019 - 10/2016
2	Immunoglobulin M (IgM)IBA 01/2017 - 04/2002
2	Controlled SubstancesIBA 11/2016 - 10/2016
2	Thalidomide (Thalomid)FDA Link 12/2014 - 04/2009
2	fludarabineIBA 02/2012 - 07/2003
2	Hemostatics (Antihemorrhagics)IBA 08/2011 - 10/2006
1	caplacizumabIBA 01/2024
1	Mevalonic Acid (Mevalonate)IBA 12/2023
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/2023
1	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 12/2023
1	Sorafenib (BAY 43-9006)FDA Link 12/2023
1	EpitopesIBA 06/2023
1	Azacitidine (5 Azacytidine)FDA Link 01/2023
1	DNA (Deoxyribonucleic Acid)IBA 01/2022
1	Lenalidomide (CC 5013)FDA Link 12/2021
1	Complement System Proteins (Complement)IBA 11/2020
1	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020
1	Tyrosine Kinase InhibitorsIBA 01/2020
1	Morphine (MS Contin)FDA LinkGeneric 01/2020

Therapy/Procedure

36	Therapeutics 04/2024 - 10/2006
7	Drug Therapy (Chemotherapy) 01/2023 - 10/2002
6	Stem Cell Transplantation 12/2021 - 07/2003
1	Transplantation 03/2024
1	Plasma Exchange 01/2024
1	Immunotherapy 06/2023
1	Glycemic Control 01/2022
1	Drug Tapering 01/2022
1	Physical Therapy Modalities (Physical Therapy Technique) 12/2021
1	Palliative Care (Palliative Therapy) 12/2020
1	Pain Management 12/2020
1	Minor Surgical Procedures (Minor Surgery) 12/2020